With propolis and myrrh. Contains Xylitol to help prevent plaque and propolis and myrrh for a healthy-feeling mouth. We use natural ingredients in innovative ways without adding anything artificial. This product does not contain saccharin, artificial sweeteners, preservatives, colors, or flavors, or animal ingredients. Tom's of Maine products are tested for safety without the use of animals. Fluoride free. Some people do not want fluoride in their toothpaste. We produce fluoride free toothpaste because we respect our customers' diverse needs and interests. What is Xylitol? Xylitol, a natural ingredient from birch trees, helps to prevent plaque buildup. Made in U.S.A.